Richardson
Predicting Parkinson's Disease Progression Using Statistical and Neural Mixed Effects Models: Comparative Study on Longitudinal Biomarkers
Tong, Ran, Wang, Lanruo, Wang, Tong, Yan, Wei
Predicting Parkinson's Disease (PD) progression is crucial, and voice biomarkers offer a non-invasive method for tracking symptom severity (UPDRS scores) through telemonitoring. Analyzing this longitudinal data is challenging due to within-subject correlations and complex, nonlinear patient-specific progression patterns. This study benchmarks LMMs against two advanced hybrid approaches: the Generalized Neural Network Mixed Model (GNMM) (Mandel 2021), which embeds a neural network within a GLMM structure, and the Neural Mixed Effects (NME) model (Wortwein 2023), allowing nonlinear subject-specific parameters throughout the network. Using the Oxford Parkinson's telemonitoring voice dataset, we evaluate these models' performance in predicting Total UPDRS to offer practical guidance for PD research and clinical applications.
- North America > United States > Texas > Dallas County > Richardson (0.04)
- North America > United States > North Carolina > Durham County > Durham (0.04)
- Europe > United Kingdom > England > Cambridgeshire > Cambridge (0.04)
- Asia > China > Zhejiang Province > Hangzhou (0.04)
- Health & Medicine > Therapeutic Area > Neurology > Parkinson's Disease (1.00)
- Health & Medicine > Therapeutic Area > Musculoskeletal (1.00)
Rainbow Noise: Stress-Testing Multimodal Harmful-Meme Detectors on LGBTQ Content
Tong, Ran, Wei, Songtao, Liu, Jiaqi, Wang, Lanruo
Hateful memes aimed at LGBTQ\,+ communities often evade detection by tweaking either the caption, the image, or both. We build the first robustness benchmark for this setting, pairing four realistic caption attacks with three canonical image corruptions and testing all combinations on the PrideMM dataset. Two state-of-the-art detectors, MemeCLIP and MemeBLIP2, serve as case studies, and we introduce a lightweight \textbf{Text Denoising Adapter (TDA)} to enhance the latter's resilience. Across the grid, MemeCLIP degrades more gently, while MemeBLIP2 is particularly sensitive to the caption edits that disrupt its language processing. However, the addition of the TDA not only remedies this weakness but makes MemeBLIP2 the most robust model overall. Ablations reveal that all systems lean heavily on text, but architectural choices and pre-training data significantly impact robustness. Our benchmark exposes where current multimodal safety models crack and demonstrates that targeted, lightweight modules like the TDA offer a powerful path towards stronger defences.
- North America > United States > Texas > Dallas County > Richardson (0.04)
- Europe > Romania > Sud - Muntenia Development Region > Giurgiu County > Giurgiu (0.04)
Cross-View Topology-Aware Graph Representation Learning
Korkmaz, Ahmet Sami, Coskunuzer, Selim, Uddin, Md Joshem
Graph classification has gained significant attention due to its applications in chemistry, social networks, and bioinformatics. While Graph Neural Networks (GNNs) effectively capture local structural patterns, they often overlook global topological features that are critical for robust representation learning. In this work, we propose GraphTCL, a dual-view contrastive learning framework that integrates structural em-beddings from GNNs with topological embeddings derived from persistent homology. By aligning these complementary views through a cross-view contrastive loss, our method enhances representation quality and improves classification performance. Extensive experiments on benchmark datasets, including TU and OGB molecular graphs, demonstrate that GraphTCL consistently outperforms state-of-the-art baselines. This study highlights the importance of topology-aware contrastive learning for advancing graph representation methods.
- North America > United States > Texas > Brazos County > College Station (0.14)
- North America > United States > Texas > Dallas County > Richardson (0.04)
- North America > United States > Georgia > Fulton County > Atlanta (0.04)
SafeCiM: Investigating Resilience of Hybrid Floating-Point Compute-in-Memory Deep Learning Accelerators
Bhattacharya, Swastik, Das, Sanjay, Menon, Anand, Kundu, Shamik, Raha, Arnab, Basu, Kanad
Deep Neural Networks (DNNs) continue to grow in complexity with Large Language Models (LLMs) incorporating vast numbers of parameters. Handling these parameters efficiently in traditional accelerators is limited by data-transmission bottlenecks, motivating Compute-in-Memory (CiM) architectures that integrate computation within or near memory to reduce data movement. Recent work has explored CiM designs using Floating-Point (FP) and Integer (INT) operations. FP computations typically deliver higher output quality due to their wider dynamic range and precision, benefiting precision-sensitive Generative AI applications. These include models such as LLMs, thus driving advancements in FP-CiM accelerators. However, the vulnerability of FP-CiM to hardware faults remains underexplored, posing a major reliability concern in mission-critical settings. To address this gap, we systematically analyze hardware fault effects in FP-CiM by introducing bit-flip faults at key computational stages, including digital multipliers, CiM memory cells, and digital adder trees. Experiments with Convolutional Neural Networks (CNNs) such as AlexNet and state-of-the-art LLMs including LLaMA-3.2-1B and Qwen-0.3B-Base reveal how faults at each stage affect inference accuracy. Notably, a single adder fault can reduce LLM accuracy to 0%. Based on these insights, we propose a fault-resilient design, SafeCiM, that mitigates fault impact far better than a naive FP-CiM with a pre-alignment stage. For example, with 4096 MAC units, SafeCiM reduces accuracy degradation by up to 49x for a single adder fault compared to the baseline FP-CiM architecture.
- North America > United States > Texas > Dallas County > Richardson (0.04)
- North America > United States > New York > Rensselaer County > Troy (0.04)
- North America > United States > New Mexico > Bernalillo County > Albuquerque (0.04)
- North America > United States > California > Santa Clara County > Santa Clara (0.04)
- Semiconductors & Electronics (0.68)
- Information Technology (0.67)
T3former: Temporal Graph Classification with Topological Machine Learning
Uddin, Md. Joshem, Changani, Soham, Coskunuzer, Baris
Temporal graph classification plays a critical role in applications such as cybersecurity, brain connectivity analysis, social dynamics, and traffic monitoring. Despite its significance, this problem remains underexplored compared to temporal link prediction or node forecasting. Existing methods often rely on snapshot-based or recurrent architectures that either lose fine-grained temporal information or struggle with long-range dependencies. Moreover, local message-passing approaches suffer from oversmoothing and oversquashing, limiting their ability to capture complex temporal structures. We introduce T3former, a novel Topological Temporal Transformer that leverages sliding-window topological and spectral descriptors as first-class tokens, integrated via a specialized Descriptor-Attention mechanism. This design preserves temporal fidelity, enhances robustness, and enables principled cross-modal fusion without rigid discretization. T3former achieves state-of-the-art performance across multiple benchmarks, including dynamic social networks, brain functional connectivity datasets, and traffic networks. It also offers theoretical guarantees of stability under temporal and structural perturbations. Our results highlight the power of combining topological and spectral insights for advancing the frontier of temporal graph learning.
- Pacific Ocean > North Pacific Ocean > San Francisco Bay (0.04)
- Oceania > Australia > New South Wales > Sydney (0.04)
- North America > United States > Texas > Dallas County > Richardson (0.04)
- (2 more...)
- Information Technology (1.00)
- Health & Medicine > Therapeutic Area > Neurology (0.49)
Revisiting Pre-trained Language Models for Vulnerability Detection
Li, Youpeng, Qi, Weiliang, Wang, Xuyu, Yu, Fuxun, Wang, Xinda
The rapid advancement of pre-trained language models (PLMs) has demonstrated promising results for various code-related tasks. However, their effectiveness in detecting real-world vulnerabilities remains a critical challenge. While existing empirical studies evaluate PLMs for vulnerability detection (VD), they suffer from data leakage, limited scope, and superficial analysis, hindering the accuracy and comprehensiveness of evaluations. This paper begins by revisiting the common issues in existing research on PLMs for VD through the evaluation pipeline. It then proceeds with an accurate and extensive evaluation of 18 PLMs on high-quality datasets that feature accurate labeling, diverse vulnerability types, and various projects. Specifically, we compare the performance of PLMs under both fine-tuning and prompt engineering, assess their effectiveness and generalizability across various training and testing settings, and analyze their robustness to a series of perturbations. Our findings reveal that PLMs incorporating pre-training tasks designed to capture the syntactic and semantic patterns of code outperform both general-purpose PLMs and those solely pre-trained or fine-tuned on large code corpora. However, these models face notable challenges in real-world scenarios, such as difficulties in detecting vulnerabilities with complex dependencies, handling perturbations introduced by code normalization and abstraction, and identifying semantic-preserving vulnerable code transformations. Also, the truncation caused by the limited context windows of PLMs can lead to a non-negligible number of labeling errors, which is overlooked by previous work. This study underscores the importance of thorough evaluations of model performance in practical scenarios and outlines future directions to help enhance the effectiveness of PLMs for realistic VD applications.
- North America > United States > Minnesota > Hennepin County > Minneapolis (0.14)
- North America > United States > California > San Francisco County > San Francisco (0.14)
- Asia > India > Karnataka > Bengaluru (0.05)
- (28 more...)
- Information Technology > Artificial Intelligence > Natural Language > Large Language Model (1.00)
- Information Technology > Artificial Intelligence > Natural Language > Chatbot (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Performance Analysis > Accuracy (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Neural Networks > Deep Learning (1.00)
- North America > United States > Texas > Dallas County > Richardson (0.04)
- North America > United States > California > Los Angeles County > Long Beach (0.04)
- North America > United States > Arizona (0.04)
- North America > United States > Texas > Brazos County > College Station (0.14)
- North America > United States > California (0.04)
- North America > United States > Washington > King County > Seattle (0.04)
- North America > United States > Texas > Dallas County > Richardson (0.04)
STONE: A Submodular Optimization Framework for Active 3D Object Detection
In particular, we address two fundamental challenges associated with active 3D object detection: data imbalance and the need to cover the distribution of the data, including LiDAR-based point cloud data of varying difficulty levels. Extensive experiments demonstrate that our method achieves state-of-the-art performance with high computational efficiency compared to existing active learning methods.
- Asia > Middle East > Jordan (0.04)
- Oceania > Australia > Western Australia > Perth (0.04)
- North America > United States > Texas > Dallas County > Richardson (0.04)
- Europe > Netherlands > North Holland > Amsterdam (0.04)
- Information Technology > Artificial Intelligence > Vision (1.00)
- Information Technology > Artificial Intelligence > Representation & Reasoning > Optimization (0.50)
- Information Technology > Artificial Intelligence > Machine Learning > Neural Networks (0.46)
- Information Technology > Artificial Intelligence > Machine Learning > Statistical Learning (0.46)
- North America > United States > Texas > Travis County > Austin (0.14)
- North America > United States > Florida > Alachua County > Gainesville (0.14)
- North America > United States > Texas > Dallas County > Richardson (0.04)
- (2 more...)
- Health & Medicine (1.00)
- Banking & Finance (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Statistical Learning (0.93)
- Information Technology > Artificial Intelligence > Machine Learning > Neural Networks > Deep Learning (0.68)
- Information Technology > Artificial Intelligence > Machine Learning > Learning Graphical Models > Directed Networks > Bayesian Learning (0.41)